Angioedema: Clinical and Etiological Aspects

Kulthanan, Kanokvalai; Jiamton, Sukhum; Boochangkool, Kanonrat; Jongjarearnprasert, Kowit

doi:https://doi.org/10.1155/2007/26438

Journal of Immunology Research

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Clinical Study | Open Access

Volume 2007 | Article ID 026438 | https://doi.org/10.1155/2007/26438

Angioedema: Clinical and Etiological Aspects

Kanokvalai Kulthanan,¹Sukhum Jiamton,¹Kanonrat Boochangkool,¹and Kowit Jongjarearnprasert²

Academic Editor: Bartholomew Dicky Akanmori

Received23 Jun 2007

Revised15 Sept 2007

Accepted05 Nov 2007

Published28 Nov 2007

Abstract

Angioedema is an abrupt swelling of the skin, mucous membrane, or both including respiratory and gastrointestinal tracts. This study aimed to report an experience of angioedema in a university hospital with respect to etiologies, clinical features, treatment, and outcome. One hundred and five patients were enrolled. About half had angioedema without urticaria. The common sites of involvement were periorbital area and lips. Forty five patients (49%) had systemic symptoms. The most common cause of angioedema was allergic angioedema. Nonsteroidal anti-inflammatory drug-induced angioedema and idiopathic angioedema were detected in 20% and 18%, respectively. Among patients with allergic angioedema, 41.7% were caused by food, 39.6% by drugs. Thirty seven patients (39%) had recurrent attacks of angioedema. Mean standard deviation (SD) number of attacks in patients with recurrent angioedema was 3.9 (2.7) (ranging from 2 to 10 times). Patients who had older age and multiple sites of skin involvement had tendency to have systemic symptoms.

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Copyright

Copyright © 2007 Kanokvalai Kulthanan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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