Table of Contents Author Guidelines Submit a Manuscript
Clinical and Developmental Immunology
Volume 2008, Article ID 327346, 8 pages
http://dx.doi.org/10.1155/2008/327346
Clinical Study

Chronic Brucellosis Patients Retain Low Frequency of CD4+ T-Lymphocytes Expressing CD25 and CD28 after Escherichia coli LPS Stimulation of PHA-Cultured PBMCs

Clinical Immunology Unit, 2nd Department of Internal Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Konstantinoupoleos Street 49, 546 42 Thessaloniki, Greece

Received 29 July 2008; Revised 20 October 2008; Accepted 19 November 2008

Academic Editor: Bernhard Fleischer

Copyright © 2008 Panagiotis Skendros et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • Mohamed G. Elfaki, and Abdullah A. Al-Hokail, “Transforming growth factor β production correlates with depressed lymphocytes function in humans with chronic brucellosis,” Microbes and Infection, vol. 11, no. 14-15, pp. 1089–1096, 2009. View at Publisher · View at Google Scholar
  • Panagiotis Skendros, Georgios Pappas, and Panagiota Boura, “Cell-mediated immunity in human brucellosis,” Microbes and Infection, vol. 13, no. 2, pp. 134–142, 2011. View at Publisher · View at Google Scholar
  • Anna Martirosyan, Edgardo Moreno, and Jean-Pierre Gorvel, “An evolutionary strategy for a stealthy intracellular Brucella pathogen,” Immunological Reviews, vol. 240, no. 1, pp. 211–234, 2011. View at Publisher · View at Google Scholar
  • Lis N. Velásquez, M. Victoria Delpino, Andrés E. Ibañez, Lorena M. Coria, M. Cruz Miraglia, Romina Scian, Juliana Cassataro, Guillermo H. Giambartolomei, and Paula Barrionuevo, “Brucella abortus induces apoptosis of human T lymphocytes,” Microbes and Infection, vol. 14, no. 7-8, pp. 639–650, 2012. View at Publisher · View at Google Scholar
  • Chun-Yan Zhang, Nan Bai, Zhu-Hong Zhang, Ning Liang, Lan Dong, Rong Xiang, and Cheng-Hu Liu, “TLR2 signaling subpathways regulate TLR9 signaling for the effective induction of IL-12 upon stimulation by heat-killed Brucella abortus,” Cellular and Molecular Immunology, vol. 9, no. 4, pp. 324–333, 2012. View at Publisher · View at Google Scholar
  • Anthony P. Cannella, Philip L. Felgner, Eduardo Gotuzzo, Alessandro Sette, Li Liang, Mayuko Saito, Renee M. Tsolis, and Joseph M. Vinetz, “Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development,” Frontiers In Cellular And Infection Microbiology, vol. 2, 2012. View at Publisher · View at Google Scholar
  • H. Wang, V. Daniel, M. Sadeghi, and G. Opelz, “Differences in the Induction of Induced Human CD4+ CD25+ FoxP3+ T-Regulatory Cells and CD3+ CD8+ CD28− T-Suppressor Cells Subset Phenotypes In Vitro: Comparison of Phorbol 12-Myristate 13-Acetate/Ionomycin and Phytohemagglutinin Stimulation,” Transplantation Proceedings, vol. 45, no. 5, pp. 1822–1831, 2013. View at Publisher · View at Google Scholar
  • N. Jain-Gupta, A. Contreras-Rodriguez, G.P. Smith, V.K. Garg, S.G. Witonsky, S. Isloor, R. Vemulapalli, S.M. Boyle, and N. Sriranganathan, “Immunotherapeutics to prevent the replication of Brucella in a treatment failure mouse model,” Vaccine, vol. 32, no. 8, pp. 918–923, 2014. View at Publisher · View at Google Scholar
  • Ebrahim Eskandari-Nasab, Mehdi Moghadampour, Habib Najibi, and Mehdi Hadadi-Fishani, “Investigation of CTLA-4 and CD86 gene polymorphisms in Iranian patients with brucellosis infection,” Microbiology and Immunology, vol. 58, no. 2, pp. 135–141, 2014. View at Publisher · View at Google Scholar
  • Mile Bosilkovskipp. 287–315, 2015. View at Publisher · View at Google Scholar
  • Kolomeietz, and Nurpeisova, “The perspectives of studying of polymorphism of genes of gamma-interferon under chronic brucellosis,” Klinichescheskaya Laboratornaya Diagnostika, vol. 2016-, no. 2, pp. 110–113, 2016. View at Publisher · View at Google Scholar
  • Kostyuchenko, Rakitina, Dejneka, Ponomarenko, Logvinenko, Sannikova, and Golub, “Perspective of in vitro lymphocytes antigenicity evaluation for the diagnostics of acute brucellosis,” Russian Journal of Infection and Immunity, vol. 7, no. 1, pp. 91–96, 2017. View at Publisher · View at Google Scholar