Do the Changes in the Serum Levels of IL-2, IL-4, TNF𝛼, and IL-6 Reflect the Inflammatory Activity in the Patients with Post-ERCP Pancreatitis?

Table 2

Comparisons of IL-2, IL-4, TNFα, IL-6, CRP and amylase levels and IL-2/IL-4 and TNFα/IL-4 ratios in the patients who underwent ERCP and control group with acute pancreatitis without ERCP.

	Patients with post-ERCP pancreatitis (𝑛=7) (1)			Patients without pancreatitis (𝑛=38) (0)			Patients with acute pancreatitis without ERCP (𝑛=10) (2)
Time (hour)	0.	12.	24.	0.	12.	24.
IL-2 (pg/mL)	15.6 (19.9)	14.3 (14.1)	12.7 (15.5)	15.1 (43.9)	12.7 (76.0)	15.1 (46.0)	11.4 (13.0)
IL-4 (pg/mL)	29.0 (69.1)	63.6 (67.5)	37.7 (56.4)^(a)	37.7 (146.8)	55.9 (83.8)	63.6 (98.0)^(b)	37.9 (58.4)^(c)
TNFα (pg/mL)	20.2 (67.8)	82.9 (81.9)^(f)	44.9 (77.5)	18.6 (66.9)^(d)	43.6 (90.5)^(g)	51.8 (72.1)	50.3 (77.5)^(e)
IL-6 (pg/mL)	1.2 (1.4)^(h)	2.4 (1.9)^(k)	3.4 (6.4)^(m)	1.6 (5.8)^(j)	2.4 (10.5)^(l)	1.9 (7.3)^(n)	5.2 (9.8)^(i)
IL-2/IL-4	0.62 (2.03)	0.33 (2.30)	0.40 (0.90)	0.44 (26.81)	0.24 (2.61)	0.23 (0.71)	0.3 (0.61)
TNFα/IL-4	0.56 (10.0)	1.31 (5.77)^(o)	1.18 (2.80)^(r)	0.67 (91.83)	0.82 (3.38)^(p)	0.81 (1.35)^(s)	1.0 (1.53)
CRP (mg/dL)	10.2 (49)	17.0 (33)	10 (47)	3.9 (212)	8.0 (395)	6.7 (342)	12.0 (42)
Amylase (U/mL)	50 (74)^(t)	1114 (1806)^(x)	460 (552)^(z)	47 (179)^(v)	131 (673)^(y)	79 (290)^(zz)	1357 (2558)^(u)

P values: .010 for (a) versus (b); .025 for (b) versus (c); .002 for (d) versus (e); .011 for (f) versus (g); .001 for (h) versus (i); <.001 for (j) versus (i); .014 for (k) versus (i); .012 for (l) versus (i); .034 for (m) versus (n); .001 for (n) versus (i); .028 for (o) versus (p); .041 for (r) versus (s); .001 for (t) versus (u); <.001 for (v) versus (u); <.001 for (x) versus (y); <.001 for (y) versus (u); <.001 for (z) versus (zz); <.001 for (zz) versus (u); .001 for (z) versus (u).