Pediatric Selective IgM Immunodeficiency

Table 4

Frequencies of comorbid diseases in patients with SIgMID. (𝑛/𝑎 = not applicable).

Disease state	Previously reported pediatric cases + 2 new cases percent (𝑛=51)	Previously reported adults cases [8] percent (𝑛=191)
Allergic rhinitis	9.8	12.6
Idiopathic angioedema	0	2.6
Idiopathic anaphylaxis	0	2.1
Asthma	18.7	24
Autoimmune disease^*	3.9	12
Bronchiectasis	0	2.6
Failure to Thrive	9.8	N/A
Gastrointestinal disease^**	15.7	12
Malignancy	0	2.6
Meningitis	7.8	0.5
Nasal polyps	0	0.5
Other infections^***	9.8	1.6
Recurrent respiratory infections	74.5	32.5
Skin disease	11.8	4.7
Thyroid disease	0	0.5
Vasomotor rhinitis	3.9	37
Fatalities	7.8	0
Asymptomatic	3.9	3.1

^∗Autoimmune thyroiditis, autoimmune anemia, autoimmune glomerulonephritis, rheumatoid arthritis, SLE.^**Includes celiac disease, inflammatory bowel disease, diarrhea syndromes.^***Nonrespiratory/nonmeningitis/nonskin.