A Possible Link between Infection with Burkholderia Bacteria and Systemic Lupus Erythematosus Based on Epitope Mimicry
Figure 5
Reaction of SLE sera and control
sera with the purified bacterial antigen. The sera were 1/100
in PBS and added into purified bacterial antigen-coated
ELISA plates and the reaction of sera antibodies with the purified
bacterial antigen were detected by goat antihuman IgG Fc fragment
specific alkaline phosphatase conjugate. The 30 SLE sera and the
control sera include 15 rheumatoid arthritis, 15 polymyositis
dematomyositis, 15 sclerodema, 15 Ro/La positive sera, and 30 normal sera. The
mean reading of 30 SLE sera bound with purified bacterial antigen was statistically
different from that of control sera ( by
unpaired -test).
