A Possible Link between Infection with Burkholderia Bacteria and Systemic Lupus Erythematosus Based on Epitope Mimicry

Figure 7

Inhibition of anti-dsDNA antibodies binding to dsDNA antigen by synthetic peptide (RAGTDEGFG). ELISA plates were coated with dsDNA (50 𝜇g/mL). Lane 1, 2, and 3 are three different patients anti-dsDNA antibodies. The light column shows the patient purified anti-dsDNA antibodies (1.25 𝜇g/100 uL) bind to dsDNA antigen, and dark column shows the patient purified anti-dsDNA antibodies (1.25 𝜇g/100 uL) mixed with synthetic peptide (3.4 𝜇g/100 uL). The data were expressed as the mean ± SD.