A Possible Link between Infection with Burkholderia Bacteria and Systemic Lupus Erythematosus Based on Epitope Mimicry
Figure 8
Reaction of SLE sera and control sera with the peptide. The
sera were diluted 1/100 in PBS and added to peptide-coated ELISA plates and the reaction of sera
antibodies with the peptide were
detected by goat antihuman IgG Fc fragment specific alkaline phosphatase conjugate. The 30 SLE sera and the
control sera include 14 rheumatoid
arthritis, 12 polymyositis dematomyositis, 14 sclerodema, 15 Ro/La positive sera, and 30 normal sera. The
mean reading of 30 SLE sera bound
with peptide was statistically different
from that of control sera ( by unpaired -test).