Use of Recombinant Antigens for the Diagnosis of Invasive Candidiasis

Table 2

Diagnostic usefulness of the detection of antibodies against Hyr1, Ece1, Als3, and Hwp1 by immunoblotting and ELISA assay [18] (PPV: positive predictive value, NPV: negative predictive value).

	Sensitivity%	Specificity%	PPV%	NPV%
Immunoblotting
Hyr1	39.1	100	100	76.3
Ece1	34.8	93.3	72.7	73.7
Als3	26.1	93.3	66.7	71.2
Hwp1	27.8	97.5	83.3	62.3
ELISA assay
Hyr1	58.3	82.2	72.4	71.2
Ece1	55.6	80.0	69.0	62.5
Als3	41.7	77.8	60.0	62.5
Hwp1	88.9	82.6	80.0	90.2