Research Article
Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers
Table 1
Clinical and demographic data of study population.
| Variable | COPD | Healthy | patients | smokers | | |
| Sex | | | Male (, %) | 133 (99.25) | 102 (96.23) | Female (, %) | 1 (0.75) | 4 (3.77) | Age (years ± STDEV) | 69.4 ± 8.9 | 63 ± 9.6 | BMI (Kg/m2) (mean ± STDEV) | 27.9 ± 5.8 | 27.7 ± 5.8 | 30 Kg/m2 (, %) | 96 (71.6) | 74 (69.8) | 30 Kg/m2 (, %) | 38 (28.3) | 32 (30.1) | Smoking status | | | Current Smokers (, %) | 53 (39.5) | 74 (69.8) | Ex Smokers (, %) | 81 (60.4) | 32 (30.1) | Pys (mean ± STDEV) | 70.9 ± 37.8 | 54.8 ± 23.3 | COPD stage | | | Mild (FEV1 80%) (, %) | 6 (4.4) | | Moderate (FEV1: 50%–79%) (, %) | 74 (55.2) | | Severe (FEV1: 30%–49%) (, %) | 40 (29.8) | | Very severe (FEV1 30%) (, %) | 14 (10.4) | | Frequency of exacerbations | | | Frequent exacerbators (, %) | 34 (27.6) | | Nonfrequent exacerbators (, %) | 89 (72.3) | |
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Abbreviations: COPD, chronic obstructive pulmonary disease; BMI, body mass index; Pys, pack years.
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