Journal of Immunology Research / 2009 / Article / Tab 1

Research Article

Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers

Table 1

Clinical and demographic data of study population.

VariableCOPDHealthy
patientssmokers
( 𝑛 = 1 3 4 ) ( 𝑛 = 1 0 6 )

Sex
 Male ( 𝑛 , %)133 (99.25)102 (96.23)
 Female ( 𝑛 , %)1 (0.75)4 (3.77)
Age (years ± STDEV)69.4 ± 8.963 ± 9.6
BMI (Kg/m2) (mean ± STDEV)27.9 ± 5.827.7 ± 5.8
< 30 Kg/m2 ( 𝑛 , %)96 (71.6)74 (69.8)
30 Kg/m2 ( 𝑛 , %)38 (28.3)32 (30.1)
Smoking status
 Current Smokers ( 𝑛 , %)53 (39.5)74 (69.8)
 Ex Smokers ( 𝑛 , %)81 (60.4)32 (30.1)
Pys (mean ± STDEV)70.9 ± 37.854.8 ± 23.3
COPD stage
 Mild (FEV1 80%) ( 𝑛 , %)6 (4.4)
 Moderate (FEV1: 50%–79%) ( 𝑛 , %)74 (55.2)
 Severe (FEV1: 30%–49%) ( 𝑛 , %)40 (29.8)
 Very severe (FEV1 < 30%) ( 𝑛 , %)14 (10.4)
Frequency of exacerbations
 Frequent exacerbators ( 𝑛 , %)34 (27.6)
 Nonfrequent exacerbators ( 𝑛 , %)89 (72.3)

Abbreviations: COPD, chronic obstructive pulmonary disease; BMI, body mass index; Pys, pack years.

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