Different Activity of the Biological Axis VEGF-Flt-1 (fms-Like Tyrosine Kinase 1) and CXC Chemokines between Pulmonary Sarcoidosis and Idiopathic Pulmonary Fibrosis: A Bronchoalveolar Lavage Study

Table 1

Demographic and lung function characteristics of patients with IPF and Pulmonary Sarcoidosis. Values are expressed as mean + SD, and age as median (range).

Characteristics	Sarcoidosis	IPF	Normal
			subjects
Number	16	18	10
Sex (Male/Female)	6/10	14/4	5/5
Age median (yrs)	53 (30–64)	69 (56–83)	40 (27–62)
Smokers/ex-	(3/0/13)	(10/2/6)	0/0/10
smokers/Nonsmokers
FEV1 (% pred)	92.1±6.7	82.6±2.6	102±13
FVC (% pred)	94.7±6.2	76.2±2.4	103±19
TLC (% pred)	87.8±3.4	65.4±4.1	95±4
DLco (% pred)	95.1±3.1	52.2±6.1	96±6
PaO2 (mmHg)	80.2±5.7	71.5±2.8	85.5±3.1
TCC×10^5 /mL	30.7±4.1	24.6±4.1	20.7±5.2
Macrophages%	70.1±8.2	86.1±2.6	94.2±1.3
Neutrophils %	3.2±3.8	6.8±2.1	3.7±2.2
Lymphocytes%	23.8±8.2	5.9±3.8	1.2±1.0
Eosinophils %	1.2±1.9	4.8±2.8	0.3±0.4

TCC: Total cell counts; FVC: Forced Vital Capacity; TLC: Total Lung Capacity; DL_CO: Diffusing Capacity for Carbon Monoxide; P𝛼O₂: Arterial Partial Pressure of Oxygen.