The Protective Effects of Ultraviolet A1 Irradiation on Spontaneous Lupus Erythematosus-Like Skin Lesions in MRL/lpr Mice

Figure 3

Dermal infiltration of mast cells in the lesional and nonlesional skin representative MRL/lpr mice. (a): nonlesional skin of non-irradiated mice. (b): spontaneous LE-like skin lesion of nonirradiated mice. (c): nonlesional skin of UVA1-irradiated (10 J/cm²) mice. In the LE-like skin lesions, the most remarkable infiltration of mast cells into dermis was detected (b). There was more number of mast cells infiltrating into the dermis of the UVA1-irradiated (10 J/cm²) mice (c), as compared to the nonirradiated mice (a). Toluidine blue stain, original magnification, ×100.

(a)

(b)

(c)