Journal of Immunology Research

Review Article

Mizoribine: A New Approach in the Treatment of Renal Disease

Table 2

Comparison between patient characteristics and laboratory findings in the three groups at the time of the first renal biopsy.
PWD ( 𝑛 = 2 1 ) PWD-pulse ( 𝑛 = 2 0 ) PWDM ( 𝑛 = 2 0 )
Age at first renal biopsy, years 1 1 . 5 ± 2 . 9 1 3 . 1 ± 4 . 3 1 2 . 9 ± 3 . 2 n.s.
Time between onset of symptoms and biopsy, months 6 . 2 ± 6 . 9 6 . 0 ± 4 . 9 5 . 5 ± 5 . 1 n.s.
Male:female ratio 1 1 ∶ 1 0 1 2 ∶ 8 1 1 ∶ 9 n.s.
Urinary protein excretion, mg/m2/hr 6 9 ± 5 5 7 2 ± 4 9 7 8 ± 6 8 n.s.
 Patients with severe proteinuria ( < 50 mg/m2/hr) 1 1 0 ± 7 9 ( 𝑛 = 1 2 ) 9 9 ± 3 6 ( 𝑛 = 1 3 ) 1 0 1 ± 5 7 ( 𝑛 = 1 2 ) n.s.
 Patients with mild proteinuria ( < 50 mg/m2/hr) 3 6 ± 1 1 ( 𝑛 = 9 ) 4 2 ± 8 ( 𝑛 = 7 ) 3 8 ± 1 2 ( 𝑛 = 8 ) n.s.
Hematuria (macroscopic)21 (13)20 (14)20 (12)n.s.
Serum albumin, g/L 3 1 ± 4 3 2 ± 6 3 0 ± 5 n.s.
Serum creatinine, 𝜇 mol/L 6 0 ± 2 2 6 4 ± 2 8 6 1 ± 2 5 n.s.
24-hour Ccr, mg/min/1.73 m2 8 4 ± 3 3 8 2 ± 3 5 7 9 ± 2 9 n.s.
n.s.: not significant.