Research Article

Changes of Immunological Profiles in Patients with Chronic Myeloid Leukemia in the Course of Treatment

Table 6

Intracellular cytokines production in activated CD3+ lymphocytes.

No.TherapyIL-2TNFalfaINF-γIL-4CPI

(1)dg, HU5644124
IFN4249183
IFN3135235
IM5360302
IM6148363
IMn.t.an.t.n.t.n.t.
DS326023*11.000

(2)dg, HU3153622
IFN1023295
IFN6966304
IFN7665325
IM6773426
IMn.t.n.t.n.t.n.t.
IM55453520*1.047

(3)dg, HU154416
IFN2446363
IFN4866503
IM2351251
IMn.t.n.t.n.t.n.t.
IM495751201.735

(4)dg, HU1720256
IFN3146298
IFN3878386
IMn.t.n.t.n.t.n.t.
IM56**6544**112.588

(5)dg, HU2221144
HU5055254
IFN3950302
IM3749248
IM5258302
IM38413051.869

(6)dg, IFN1117222
IFN3651323
IM4855355
DS2059453
DS184437*192.269

(7)dg, HU5146343
HU5242302
HU5268555
IMn.t.n.t.n.t.n.t.
IM525334251.223

(8)dg, IM4244232
IM3844192
IM1625135
IMn.t.n.t.n.t.n.t.
IMn.t.n.t.n.t.n.t.
IM41372330.937

(9)dg, IM234451
IMn.t.n.t.n.t.n.t.
IM317457132.134
(10)dg, IMn.t.n.t.n.t.n.t.
IM2732141
IM3854243
IM50**5130**6**1.827

(11)dg, HUn.t.n.t.n.t.n.t.
DS5962231
DSn.t.n.t.n.t.n.t.n.t.

CPI:Cytokine Production Index—a ratio between the sum of cytokine producing cells ls as detected in the last sample and the sum of cytokine producing cells in the first sample available.
an.t.:not tested.
* ,  ** for trend with time.