Developmental Profiles of Mucosal Immunity in Pre-school Children

Table 2

Salivary immunological parameters, reported as geometric mean and 95% confidence interval (CI), at each assessment point during the pre-school year.

	Saliva collection time
	1	2	3	4	5
	February (summer end) geometric mean (95% CI)	April (autumn) geometric mean (95% CI)	July (winter) geometric mean (95% CI)	September (spring) geometric mean (95% CI)	December (presummer) geometric mean (95% CI)
IgA (mg/L)	21.83 (18.99–25.10)	21.07 (18.20–24.40)	30.27 (25.72–35.61)	20.65 (17.48–24.39)	22.12 (18.85–25.97)
IgG (mg/L)	2.99 (2.34–3.82)	2.89 (2.29–3.66)	2.32 (1.86–2.91)	3.03 (2.26–4.06)	2.87 (2.16–3.82)
IgM (mg/L)	0.87 (0.64–1.17)	0.96 (0.73–1.26)	0.81 (0.63–1.04)	1.04 (0.83–1.31)	1.10 (0.81–1.48)
E. coli-specific IgA antibody (EU/mL)	0.11 (0.09–0.14)	0.08 (0.06–0.09)	0.10 (0.09–0.12)	0.12 (0.09–0.16)	0.11 (0.09–0.13)