Correlation between Clinicopathology and Expression of Heat Shock Protein 72 and Glycoprotein 96 in Human Esophageal Squamous Cell Carcinoma

Table 2

Relationship between clinicopathology and immunoreactivity of HSP72 and gp96 in esophageal squamous cell carcinomas.

Pathologic types		HSP72		gp96
	𝑛	− (%)	+ (%)	− (%)	+ (%)
Tissues adjacent	120	90 (75.0)	30 (25.0)	96 (80.0)	24 (20.0)
to cancers
Esophageal carcinomas^a	120	8 (6.7)	112 (93.3)	18 (15.0)	102 (85.0)
Tumor Differentiation^b
Well differentiated	67	6 (9.0)	61 (91.0)	11 (16.4)	56 (83.6)
Moderately differentiated	29	2 (6.9)	27 (93.1)	4 (13.8)	25 (86.2)
Poorly differentiated	24	0 (0)	24 (100)	3 (12.5)	21 (87.5)
Lymph node metastasis^c
yes	98	0 (0)	98 (100)	0 (0)	98 (100)
no	22	8 (36.4)	14 (63.6)	18 (81.8)	4 (18.2)
Remote metastasis^d
yes	56	0 (0)	56 (100)	0 (0)	56 (100)
no	64	8 (12.5)	56 (87.5)	18 (28.1)	46 (71.9)
pT classification^e
T1	20	4 (20)	16 (80)	6 (30)	14 (70)
T2	22	2 (9.1)	20 (90.9)	3 (13.6)	17 (77.3)
T3	40	2 (5)	38 (95)	5 (12.5)	35 (87.5)
T4	38	2 (5.26)	38 (100)	2 (5.3)	36 (94.7)
pN classification^f
N0	22	8 (36.4)	14 (63.6)	18 (81.8)	4 (18.2)
N1	45	0 (0)	45 (100)	0 (0)	45 (100)
N2	53	0 (0)	53 (100)	0 (0)	53 (100)
pM classification^h
M0	64	8 (12.5)	56 (87.5)	18 (28.1)	46 (71.9)
M1	56	0 (0)	56 (100)	0 (0)	56 (100)

^a𝑃<.01, ^b𝑃<.01, versus tissues adjacent to cancers; ^c𝑃<.05, ^d𝑃<.05, versus non-metastasis groups; ^e𝑃<.05, pT1,T2 versus pT3,T4; ^f𝑃<.05, pN1,N2 versus pN0; ^h𝑃<.05, pM1 versus pM0.