Cytokine Production by Peripheral Blood CD4⁺ and CD8⁺ T Cells in Atopic Childhood Asthma

Table 2

Percentage of CD4⁺ and CD8⁺ T cells spontaneously producing IL-2, IL-4, IL-10, IL-13, IFN-γ, and TNF-α.

	CD4^+/IL-2^+	CD4^+/IL-4^+	CD4^+/IL-10^+	CD4^+/ IL-13^+	CD4^+/IFN-γ ^+	CD4^+/TNF-α ^+
Asthma 𝑛=40	2.75±0.17	3.45±0.24	3.78±0.26	3.78±0.2	3.0±0.18	2.92±0.15
Controls 𝑛=18	3.11±0.31	2.83±0.23	4.58±0.71	3.33±0.22	2.5±0.26	3.0±0.35
	CD8^+/IL-2^+	CD8^+/IL-4^+	CD8^+/IL-10^+	CD8^+/IL-13^+	CD8^+/IFN-γ ^+	CD8^+/TNF-α ^+
Asthma 𝑛=40	3.4±0.21	3.45±0.19^∗	3.73±0.31	4.4±0.34	3.1±0.19	3.53±0.26
Controls 𝑛=18	3.58±0.36	2.75±0.13	4.0±0.48	3.42±0.19	3.08±0.4	3.0±0.28

𝑃-values from Mann-Whitney U-test
^∗𝑃<.05
Data as shown as mean ± SE.