Atopic Dermatitis-Like Skin Lesions Reduced by Topical Application and Intraperitoneal Injection of Hirsutenone in NC/Nga Mice
Figure 2
Progression of clinical dermatitis score for different intervention groups during the 4 weeks treatment period. Clinical findings were scored at 1-week intervals. (a) Representative clinical feature of NC/Nga mice skin. (b) HIR treatment significantly lowered total clinical severity scores. Data shown are mean ± S.D. of changes in total clinical dermatitis scores for face, ears, nose, and back. HIR: Hirsutenone, DEX: dexamethasone, Base: Baseline, HDC: hydrocortisone cream, INJ: injection, APP: application. ∗ compared with the PBS group. # compared with the Base group. /group.
