In-Hospital Mortality of Disseminated Tuberculosis in Patients Infected with the Human Immunodeficiency Virus
Table 2
In-hospital mortality among HIV-infected patients with disseminated tuberculosis.
In-hospital death
Yes
No
Total
Male
22 (78.5)
37 (71)
59 (74)
Median Age in years (range)
33 (16–73)
33 (14–70)
33
Concomitant opportunistic infection
3 (10.5)
9 (17.5)
12 (15)
ICU admission
14 (50)
4 (7.5)
18 (22.5)
.01
Fever at admission
17 (60.5)
50 (96)
67 (84)
.01
Median alkaline phosphatase (U/L)
601
401
426
(range)
(62–2539)
(50–4991)
Median ALT (U/L)
47
43
43
(range)
(10–389)
(9–429)
Median AST (U/L)
100
58
69
(range)
(18–544)
(12–1575)
Median LDH (U/L)
730
723
725
(range)
(227–1627)
(172–2329)
Median Bilirrubin (mg/dL)
1.3
0.7
0.8
(range)
(0.3–8.1)
(0.3–5.2)
Median Hematocrit (%)
23
27
26
(range)
(13–34)
(8–43)
Median Hemoglobin (g/dL)
7.6
8.9
8.8
(range)
(5.5–11.1)
(4.6–13.4)
Median Leukocytes (109/L)
4.4
5.1
4.8
(range)
(0.5–10.2)
(0.5–31.6)
Median Albumin (g/dL)
2.2
2.7
2.6
.01
(range)
(1.4–3.1)
(1.7–4.0)
Median Creatinine (mg/dL)
0.9
0.8
0.9
(range)
(0.2–2.9)
(0.4–1.7)
Median CD4 (cells/mcL)
36
39
39
(range)
(1–327)
(2–469)
In-hospital HAART1
6 (22.2)
7 (14.3)
13 (17.1)
Appropriate initial TB therapy
23 (82.1)
50 (96.2)
73 (91.2)
Median time to therapy (days)
6.5
7.0
7.0 ()
(range)
(0.0–49.0)
(0.0–53.0)
Note. Data are no. (%) of patients, unless otherwise indicated. ICU, Intensive care unit; AFB, acid fast bacilli; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; HAART, highly active antiretroviral therapy; TB, tuberculosis. 1In-hospital HAART means the prescription of HAART during hospital stay, independent of previous ART use.
