Research Article

Serum Positive for the Autoantibody against the -Adrenoceptor from Chinese Patients with Congestive Heart Failure Decreases in Mouse Cardiac Myocytes

Figure 3

Different concentrations of AAB-β 1-positive serum (dilution ranging from 1 : 100, 1 : 50, 1 : 20 to 1 : 10) on the outward K+  currents at a voltage of 50 mV: showed no changes at different concentrations of AAB-β 1-positive serum (a). A low concentration of AAB-β 1-positive serum (1 : 100) had a small inhibitory effect on (b, c). However, AAB-β 1-positive serum at 1 : 10, 1 : 20, and 1 : 50 significantly decreased ( , b, c). Additionally, there were no significant differences in currents at 1/10 and 1/20 AAB-β 1-positive serum treatment (b, c). AAB-β 1-positive serum had no effect on the I-V relationship at any concentration (a, b). .
143517.fig.003a
(a)
143517.fig.003b
(b)
143517.fig.003c
(c)