Detection of N-Glycolyl GM3 Ganglioside in Neuroectodermal Tumors by Immunohistochemistry: An Attractive Vaccine Target for Aggressive Pediatric Cancer
Immunohistochemical detection of NeuGc-GM3 ganglioside in neuroectodermal tumors. (a) Neuroblastoma (NMYC-amplified). (b) Ewing sarcoma family of tumors (ESFT). (c) Negative isotype control staining (mouse IgG1) in neuroblastoma. (d) No expression in nontumoral neural tissue. Original magnification 400X (a, b and c), 100X (d), 1,000X (insets).
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