Serum and Salivary IgE, IgA, and IgG₄ Antibodies to Dermatophagoides pteronyssinus and Its Major Allergens, Der p1 and Der p2, in Allergic and Nonallergic Children

Figure 1

(a) Levels of IgE antibodies to Dermatophagoides pteronyssinus (Dpt) crude extract and its major allergens (Der p1 and Der p2) in serum samples from allergic (𝑛=72) and nonallergic (𝑛=14) infants. Data are expressed in ELISA index (EI) and the geometric mean for each allergen is indicated by horizontal bars. The dashed line indicates the cutoff of the reaction (EI>1.2). ***𝑃<0.0001 as determined by the Mann-Whitney 𝑈 test. (b), (c), and (d) Correlation between levels of serum IgE anti-Dpt versus anti-Der p1 (b), IgE anti-Dpt versus anti-Der p2 (c), and IgE anti-Der p1 versus anti-Der p2 (d). The Spearman correlation coefficient (𝑟) and statistical significance are also indicated.

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