Serum and Salivary IgE, IgA, and IgG₄ Antibodies to Dermatophagoides pteronyssinus and Its Major Allergens, Der p1 and Der p2, in Allergic and Nonallergic Children

Figure 5

Levels of IgG4 antibodies to Dermatophagoides pteronyssinus (Dpt) crude extract and its major allergens (Der p1 and Der p2) in serum (a) and saliva (b) samples from allergic (𝑛=72) and nonallergic (𝑛=14) infants. Data are expressed in ELISA index (EI) and the geometric mean for each allergen is indicated by horizontal bars. The dashed line indicates the cut off of the reaction (EI>1.2) and percentages of positive IgG4 samples for each allergen are also indicated. *𝑃<0.05; **𝑃<0.001; ***𝑃<0.0001 as determined by the Mann-Whitney 𝑈 test; ^# Statistical significance determined by the Fisher exact test (𝑃<0.05).

(a) Serum

(b) Saliva