Immunopathology of Postprimary Tuberculosis: Increased T-Regulatory Cells and DEC-205-Positive Foamy Macrophages in Cavitary Lesions

Table 2

Percentage of cells positive for immunological markers.

	Primary TB	Postprimary TB	Postprimary TB
	Granuloma	Lipid pneumonia	Cavitary lesion
Marker
CD4	30.7 ± 4.1	10.1 ± 3.1^a	23.1 ± 4.6^a,b
CD8	17.8 ± 4.2	19.6 ± 3.8	27.7 ± 7.1
CD20	2.0 ± 0.5	2.3 ± 0.7	7.8 ± 1.2^a,b
CD68	49.4 ± 5.0	64.0 ± 12.5	55.1 ± 14.8
DEC-205	9.0 ± 3.5	36.1 ± 8.5^a	27.8 ± 8.5^a
Foxp3	4.8 ± 1.1	5.2 ± 1.2	14.8 ± 4.3^a,b

Images of the different tissue manifestation of TB were taken using the 10x objective from at least 5 regions of multiple cases. The total number of cells was determined using the hematoxylin stain. The data are presented as the percentage of cells positive for a given marker, ±SD.
^aP <  .05, comparison to granuloma.
^bP <  .05, comparison to lipid pneumonia.