Expansion of CD16-Negative Natural Killer Cells in the Peripheral Blood of Patients with Metastatic Melanoma

Table 1

Absolute NK cells counts and plasma cytokine/growth factor levels in patients with metastatic melanoma. Cell counts are measured in cells ×10⁹ per liter, and plasma cytokines/growth factors are measured in picograms/milliliter.

	Median	Minimum	Maximum
Absolute NK cell count	0.64	0.13	1.66
Absolute CD16+ NK	0.56	0.03	1.53
Absolute CD16− NK	0.11	0.01	0.50
IL-1b	3.22	0.00	1216.46
IL-1ra	80.90	0.19	4130.51
IL-2	7.42	0.00	463.38
IL-4	3.95	0.00	129.84
IL-5	1.02	0.00	17.22
IL-6	11.83	0.41	2307.25
IL-7	5.38	0.58	250.24
IL-8	11.45	0.06	2439.86
IL-10	4.22	0.00	175.74
IL-12p70	6.88	0.00	1637.86
IL-13	6.07	0.00	162.68
IL-15	9.22	0.00	709.06
IL-17	6.36	0.00	96.60
TNF-α	13.28	0.00	439.51
G-CSF	16.22	0.42	622.01
GM-CSF	70.58	0.00	419.91
IFN-γ	8.85	0.00	325.81
IP-10	77.56	0.73	3679.56
MCP-1	46.28	0.02	19679.10
MIP-1a	8.11	0.00	907.85
MIP-1b	79.34	0.27	13000.21
VEGF	15.32	0.00	161.15