Review Article

Innate Immune Effectors in Mycobacterial Infection

Figure 1

Recognition of mycobacteria by Toll-like receptors. TLR2 recognizes several mycobacterial-derived components. TLR9 recognizes mycobacterial DNA including the CpG motif within endosomal compartments. TLR-dependent recognition of mycobacteria induces activation of signaling pathways via the adaptor molecule MyD88, leading to activation of gene expression.
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