Table of Contents Author Guidelines Submit a Manuscript
Clinical and Developmental Immunology
Volume 2011, Article ID 516219, 11 pages
http://dx.doi.org/10.1155/2011/516219
Research Article

Newborn Mice Vaccination with BCG.HIVA222 + MVA.HIVA Enhances HIV-1-Specific Immune Responses: Influence of Age and Immunization Routes

1AIDS Research Unit, Hospital Clínic/IDIBAPS-HIVACAT, University of Barcelona, Calle Villarroel 170, 08036 Barcelona, Spain
2MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford University and The John Radcliffe, Oxford OX3 9DS, UK
3Unitat Tuberculosi Experimental, Institut “Germans Trias i Pujol”, Carretera del Canyet S/N, Badalona 08916, Barcelona, Spain

Received 15 September 2010; Accepted 1 February 2011

Academic Editor: Eiji Matsuura

Copyright © 2011 Narcís Saubi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [15 citations]

The following is the list of published articles that have cited the current article.

  • Richard Hopkins, Anne Bridgeman, Charles Bourne, Alice Mbewe-Mvula, Jerald C. Sadoff, Gerald W. Both, Joan Joseph, John Fulkerson, and Tomáš Hanke, “Optimizing HIV-1-specific CD8+ T-cell induction by recombinant BCG in prime-boost regimens with heterologous viral vectors,” European Journal of Immunology, vol. 41, no. 12, pp. 3542–3552, 2011. View at Publisher · View at Google Scholar
  • Narcís Saubi, Alice Mbewe-Mvula, Ester Gea-Mallorqui, Maximillian Rosario, Josep Maria Gatell, Tomáš Hanke, and Joan Joseph, “Pre-clinical development of BCG.HIVA CAT, an antibiotic-free selection strain, for HIV-TB pediatric vaccine vectored by Lysine Auxotroph of BCG,” PLoS ONE, vol. 7, no. 8, 2012. View at Publisher · View at Google Scholar
  • Jean-Pierre Amorij, Gideon F.A. Kersten, Vinay Saluja, Wouter F. Tonnis, Wouter L.J. Hinrichs, Bram Slütter, Suzanne M. Bal, Joke A. Bouwstra, Anke Huckriede, and Wim Jiskoot, “Towards tailored vaccine delivery: Needs, challenges and perspectives,” Journal of Controlled Release, vol. 161, no. 2, pp. 363–376, 2012. View at Publisher · View at Google Scholar
  • Rosamund Chapman, Enid Shephard, Helen Stutz, Nicola Douglass, Vasan Sambandamurthy, Irene Garcia, Bernhard Ryffel, William Jacobs, and Anna-Lise Williamson, “Priming with a recombinant pantothenate auxotroph of mycobacterium bovis bcg and boosting with mva elicits HIV-1 gag specific CD8+ T cells,” PLoS ONE, vol. 7, no. 3, 2012. View at Publisher · View at Google Scholar
  • Juliana Falivene, Maria Paula Del Medico Zajac, Maria Fernanda Pascutti, Ana Maria Rodriguez, Cynthia Maeto, Beatriz Perdiguero, Carmen E. Gomez, Mariano Esteban, Gabriela Calamante, and Maria Magdalena Gherardi, “Improving the MVA Vaccine Potential by Deleting the Viral Gene Coding for the IL-18 Binding Protein,” Plos One, vol. 7, no. 2, 2012. View at Publisher · View at Google Scholar
  • Kara Jensen, Myra Grace dela Pena, Robert L. Wilson, Uma Devi K. Ranganathan, William R. Jacobs, Glenn Fennelly, Michelle Larsen, Koen K.A. Van Rompay, Pamela A. Kozlowski, and Kristina Abel, “A neonatal oral Mycobacterium tuberculosis-SIV prime/intramuscular MVA-SIV boost combination vaccine induces both SIV and Mtb-specific immune responses in infant macaques,” Trials in Vaccinology, 2013. View at Publisher · View at Google Scholar
  • Muhammed O. Afolabi, Jorjoh Ndure, Abdoulie Drammeh, Fatoumatta Darboe, Shams-Rony Mehedi, Sarah L. Rowland-Jones, Nicola Borthwick, Antony Black, Gwen Ambler, Grace C. John-Stewart, Marie Reilly, Tomas Hanke, and Katie L. Flanagan, “A Phase I Randomized Clinical Trial of Candidate Human Immunodeficiency Virus type 1 Vaccine MVA.HIVA Administered to Gambian Infants,” Plos One, vol. 8, no. 10, 2013. View at Publisher · View at Google Scholar
  • Beatrice O. Ondondo, “The influence of delivery vectors on HIV vaccine efficacy,” Frontiers in Microbiology, vol. 5, 2014. View at Publisher · View at Google Scholar
  • Irene N. Njuguna, Gwen Ambler, Marie Reilly, Beatrice Ondondo, Mercy Kanyugo, Barbara Lohman-Payne, Christine Gichuhi, Nicola Borthwick, Antony Black, Shams-Rony Mehedi, Jiyu Sun, Elizabeth Maleche-Obimbo, Bhavna Chohan, Grace C. John-Stewart, Walter Jaoko, and Tomáš Hanke, “PedVacc 002: A phase 1 randomized clinical trial of MVA.HIVA vaccine administered to infants born to human immunodeficiency virus type 1-positive mothers in Nairobi,” Vaccine, 2014. View at Publisher · View at Google Scholar
  • Narcís Saubi, Ester Gea-Mallorquí, Pau Ferrer, Carmen Hurtado, Sara Sánchez-Úbeda, Yoshiki Eto, Josep M Gatell, Tomáš Hanke, and Joan Joseph, “Engineering new mycobacterial vaccine design for HIV–TB pediatric vaccine vectored by lysine auxotroph of BCG,” Molecular Therapy - Methods & Clinical Development, vol. 1, pp. 14017, 2014. View at Publisher · View at Google Scholar
  • C. Giles, T. Vanniasinkam, S. Ndi, and M. D. Barton, “Rhodococcus equi (Prescottella equi) vaccines; the future of vaccine development,” Equine Veterinary Journal, vol. 47, no. 5, pp. 510–518, 2015. View at Publisher · View at Google Scholar
  • Aakash Mahant, Narcís Saubi, Yoshiki Eto, Núria Guitart, Josep M ª Gatell, Tomáš Hanke, and Joan Joseph, “ Preclinical Development of BCG.HIVA 2auxo.int , Harboring an Integrative Expression Vector, for a HIV-TB Pediatric vaccine. Enhancement of Stability and Specific HIV-1 T-cell Immunity ,” Human Vaccines & Immunotherapeutics, pp. 00–00, 2017. View at Publisher · View at Google Scholar
  • Kara Jensen, Michael G. Hudgens, Angela Amedee, Pamela A. Kozlowski, Jacob D. Estes, Michelle Larsen, Kristina De Paris, Michael Piatak, Kelli Oswald, Katie R. Mollan, Jeffrey D. Lifson, Koen K. A. Van Rompay, Myra Grace Dela Pena-Ponce, Rebecca Shoemaker, William R. Jacobs, Glenn Fennelly, and Carissa Lucero, “Balancing trained immunity with persistent immune activation and the risk of simian immunodeficiency virus infection in infant macaques vaccinated with attenuated mycobacterium tuberculosis or mycobacterium bovis BCG vaccine,” Clinical and Vaccine Immunology, vol. 24, no. 1, 2017. View at Publisher · View at Google Scholar
  • Kara Jensen, Michael G Hudgens, Angela Amedee, Pamela A Kozlowski, Jacob D Estes, Jeffrey D Lifson, Koen K A Van Rompay, Michelle Larsen, Kristina De Paris, Myra Grace Dela Pena-Ponce, Michael Piatak, Rebecca Shoemaker, Kelli Oswald, William R Jacobs, Glenn Fennelly, Carissa Lucero, and Katie R Mollan, “Balancing Trained Immunity with Persistent Immune Activation and the Risk of Simian Immunodeficiency Virus Infection in Infant Macaques Vaccinated with Attenuated Mycobacterium tuberculosis or Mycobacterium bovis BCG Vaccine.,” Clinical and vaccine immunology : CVI, vol. 24, no. 1, 2017. View at Publisher · View at Google Scholar
  • Esther Broset, Narcís Saubi, Núria Guitart, Nacho Aguilo, Santiago Uranga, Athina Kilpeläinen, Yoshiki Eto, Tomáš Hanke, Jesús Gonzalo-Asensio, Carlos Martín, and Joan Joseph-Munné, “MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice,” Molecular Therapy - Methods & Clinical Development, vol. 13, pp. 253–264, 2019. View at Publisher · View at Google Scholar