Innate Immune Sensors and Gastrointestinal Bacterial Infections

Figure 2

The interaction of colonic microbiota and pattern recognition receptors in normal colonic epithelium and in the epithelium of inflammatory bowel disease. The schematic representation summarizes the key abnormalities at the level of the intestinal lumen, surface PRRs, and intracellular PRRs in inflammatory bowel disease and compares and contrasts them with normal homeostatic interactions.