Research Article
Recombinant HBHA Boosting Effect on BCG-Induced Immunity against Mycobacterium tuberculosis Infection
Table 1
Differential recombinant HBHA boosting effect of BCG-induced protective immunity in BALB/c newborn mice against M. tuberculosis H37Rv infection as measured by reduced bacterial load in spleen and lungs.
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aData are represented as mean ± standard deviations of the log10-transformed bacterial (CFUs) of M. tuberculosis per organ; bintranasal challenge; caerosol challenge. Protection is calculated with respect to control of vaccination (BCG) and with respect to PBS-immunized newborn mice (control). The data reported are ignificant at with respect to control mice and **significant at with respect to BCG control of vaccination with no boost. One representative of a total of two independent experiments is shown. |