Clinical Study
Immune Dysregulation after Cardiothoracic Surgery and Incidental Thymectomy: Maintenance of Regulatory T Cells despite Impaired Thymopoiesis
Table 1
Characteristics of subjects.
| | No Surgery | Prior Surgery: high TREC | Prior Surgery: low TREC | | (10-CHD; 5-healthy adults) | | |
| Age at evaluation | 16.47 (0.2–34.9) | 22.6 (1.00–35.7) | 18.6 (2.00–34.5) | Healthy adults | 26.1 (20.0–29.0) | | | CHD | 12.0 (0.2–34.9) versus Healty adults | | | Age at 1st surgery | | 6.6 (0–28.4) | 2.5 (0–13.8) versus High TREC | Time since 1st surgery | | 16.0 (0.2–34.7) | 16.1 (1.9–34.0) | Age at last surgery | | 12.2 (0.01–34.71) | 1.4 (0.03–24.4) | Time since last surgery | | 10.4 (0.1–33.1) | 11.0 (0.8–24.3) | Number of surgeries (number of subjects) | | | | 0 | 15 (100%) | | | 1 | | 16 (50%) | 5 (29%) | ≥2 | | 16 (50% | 12 (71%) | Age at initial surgery (number of subjects) | | | | <2 years | | 13 (41%) | 12 (71%) | >2 years | | 19 (59%) | 5 (29%) | Residual thymus (present : absent) | 6 : 0 | 12 : 10 | 2 : 9 |
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Surgery = midline stemotomy. Kruskal-Wallis test Chi-Square test . Mann-Whitney test.
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