Suppressors of Cytokine Signaling 3 Expression in Eosinophils: Regulation by PGE2 and Th2 Cytokines
Figure 4
SOCS3 mRNA expression in Th2-stimulated eosinophils from healthy controls, asthmatics, and NAEB patients. Eosinophils from healthy controls, asthmatics, and NAEB patients were cultured with 10 ng/mL of IL-4 or IL-5, or IL-13 during 60 min. SOCS3 mRNA was measured by real-time quantitative PCR. The results are expressed as a fold induction relative to untreated eosinophils, and significant differences are indicated. Data represent the geometric mean ± SD from three individuals, and each measure was performed in triplicate.
