Journal of Immunology Research / 2012 / Article / Fig 1

Review Article

Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

Figure 1

Different implications of maternal and paternal IgE levels for antenatal IgE level and postnatal IgE production at different ages in our cohort study. (a), (c): Maternal (Ma) atopy, defined as IgE > 150 kU/L, but not paternal (Pa) atopy, significantly affected antenatal IgE production, reflected by CBIgE elevation (>0.5 kU/L). (b), (d): Maternal atopy (solid circles) was significantly associated with log-transformed IgE levels at 6 months (6 m), 18 months (18 m), 3 years (36 m), and 6 years (6 y) of age, whereas paternal atopy (open circles) was only significantly associated with log-transformed levels at 3 and 6 years of age.

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