Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development
Different implications of maternal and paternal IgE levels for antenatal IgE level and postnatal IgE production at different ages in our cohort study. (a), (c): Maternal (Ma) atopy, defined as IgE > 150 kU/L, but not paternal (Pa) atopy, significantly affected antenatal IgE production, reflected by CBIgE elevation (>0.5 kU/L). (b), (d): Maternal atopy (solid circles) was significantly associated with log-transformed IgE levels at 6 months (6 m), 18 months (18 m), 3 years (36 m), and 6 years (6 y) of age, whereas paternal atopy (open circles) was only significantly associated with log-transformed levels at 3 and 6 years of age.
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