Journal of Immunology Research / 2012 / Article / Tab 1

Review Article

Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

Table 1

Does CBIgE elevation predict allergy?

ParametersPopulation studied, countryReference

Parameters correlated with elevated CBIgE

 Skin-prick test at age 4 yr1456, England[10]
 Allergic sensitization and recurrent wheezing at age 7 yr380 high-risk newborns, Canada[13]
 Allergic sensitization at 4 and 10 yr and asthma at 10 yr1456, USA[14]
 Skin-prick test at age 5 yr, allergic rhinoconjunctivitis at age 20 yr, and total IgE  at ages 11 and 20 yr200, Finland[15]
 High IgE and allergic sensitization between the ages of 18 and 24 months1884, Sweden[11]
 Total IgE and allergic diseases before 5 years of age1884, USA[12]

Parameters not correlated with elevated CBIgE

 No significant association with recurrent wheezing1314, Germany[16]
 Not better than family history to predict infant atopy2814, USA[17]
 Family history of atopy far more sensitive than CBIgE1111, UK[18]

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