Journal of Immunology Research / 2012 / Article / Tab 2

Review Article

Different Implications of Paternal and Maternal Atopy for Perinatal IgE Production and Asthma Development

Table 2

Effect of parental background on IgE production and asthma development.

Maternal backgroundPaternal background

GeneMaternal antioxidant gene polymorphisms: GSTP1 [51] GSTM1 and GSTT1 [52]
Polymorphism of the beta-chain of high-affinity IgE receptor (FceRI-beta) [53], and 11q13 allele [54]
An allele at chromosome 7p [50]

EnvironmentMaternal asthma [3439]
Fetal exposure to tobacco smoke, household allergens, and latex and/or biocides [5863, 65]
Fetal exposure to traffic air pollution [64]
Maternal prenatal exposure to farm, farm animals, and cat or dog [58, 66, 68]
Mediterranean diet, fish intake, fatty acid status, and folic acid supplements during pregnancy [24, 69, 72, 73]
Paternal asthma [4043]
Paternal occupational flour dust exposure [65]

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