Immunological and Nonimmunological Effects of Indoleamine 2,3-Dioxygenase on Breast Tumor Growth and Spontaneous Metastasis Formation

Figure 4

In vitro proliferation and western blot analysis ATM and SFN proteins in Ido1+ and Ido1− breast tumor cells. (a) Analysis of ³H thymidine incorporation and (b) cell counting using Cellomics Array Scan in 4T1/vector, 4T1/Ido1−, NT-5/vector, and NT-5/Ido1+ cells. (c) Western blots analysis of ATM and (d) SFN (14-3-3 sigma protein) expression in 4T1/vector, 4T1/Ido1−, NT-5/vector, and NT-5/Ido1+ cells.

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