HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro

Figure 3

The effect of miR-H6 on IL-6 release in medium. HCE cells were transfected with miR-H6 and infected with MOI 0.1 of HSV-1 after 24 h posttransfection (a) or without viral infection (b). The IL-6 level in medium was measured at indicated time p.i. by ELISA. *Statistical difference between HCE cells transfected with miR-H6 mimics and mock or HSV-1 alone (𝑃<0.01); ^+/++statistical difference between normal HCE cells and mock or HSV-1 alone (⁺𝑃<0.05; ⁺⁺𝑃<0.01).

(a)

(b)