Herpes Simplex Virus-2 Glycoprotein Interaction with HVEM Influences Virus-Specific Recall Cellular Responses at the Mucosa
Figure 3
HSV-specific CD8+ T cell frequencies do not differ in lymphocytes isolated from (a) draining lymph nodes from groups of mice primed with viruses than can (HSV-2/gD-βgal, left, open circles) or cannot (HSV-2/gD-Δ7-15-βgal, right, filled triangles) engage HVEM, but are significantly different at the (b) vaginal mucosa. Symbols show data from individual mice, with the horizontal line designating the mean for each experimental group. Data are pooled from three independent experiments with 3-4 mice per group.
