Indirect Effects of Oral Tolerance Inhibit Pulmonary Granulomas to Schistosoma mansoni Eggs
Figure 3
Re-exposure of orally tolerant animals to the tolerated antigen block enlargement of granuloma area. The area of granulomas at days 1, 5, 11 and 14 after i.v. injection of eggs in nonimmunized mice (granuloma group, open bars), OVA immune controls (hatched bars), and OVA-orally tolerant (black bars). Data represent mean ± SEM (five mice/group). tolerant versus immune and tolerant versus granuloma.
