Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensu lato in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis

Table 2

The OF induced cytokine secretion in PBMCs by Luminex.

Cytokine	Exposed asymptomatic	Previous clinical LB	Controls
IL-1β	309 (183–846)	341 (132–1223)	340 (162–800)
IL-6	6805 (3528–12749)	7304 (3281–50303)	7335 (2578–12324)
IL-10	130 (38–442)	129 (42–572)	123 (37–684)
IL-12(p70)	1 (0-1)	1 (0-1)	1 (0-1)
TNF	676 (241–2311)	561 (209–1724)	628 (226–1373)

NOTE. The data referred to in the table is given as median values in pg/mL (range in parenthesis).
OF: outer surface protein enriched fraction; PBMCs: peripheral blood mononuclear cells; LB: Lyme Borreliosis; IL = interleukin; TNF: tumour necrosis factor.