Hematopoietic Stem Cell Transplantation for Systemic Lupus Erythematosus

Table 1

A synthesis of the first case of SE performed in Genoa, with a followup of 16 years.

Year	Age	Clinical symptoms	Laboratory tests	Therapy
1983	33	Arthralgias, fever	ANA+ Wasserman test+	NSAIDs
1985	35	Exudative pleuritis pericarditis		Prednisone bolus plus tapered doses
1995	36	Nephropathy proteinuria >10 g/day	ANA 1: 160, ds-DNA pos, LE phenomenon pos, CH50 620, proteinuria, hematuria	CY, prednisone bolus, AZA, auto-HSCT
2000	50	Asthenia, proteinuria 2 g/24 h	ANA 1: 320 homogeneous, ds-DNA neg, complement normal, proteinuria, hematuria	Mycophenolate mofetil 2 g/day, prednisone 1 mg/kg
2005	55	Tendinitis	ANA 1: 320 homogeneous, ds-DNA neg, LE phenomenon neg, complement normal, proteinuria 0.5 g/24 h	Mycophenolate mofetil 2 g/day, prednisone 2 mg/kg plus tapered doses
2008	58	Facial erythema	ANA 1: 320 homogeneous, ds-DNA neg, LE phenomenon neg, complement normal, proteinuria 0.5 g/24 h	Mycophenolate mofetil 2 g/day, prednisone 0.5 mg/kg, hydroxichloroquine
2012	62	Disease quiescent, the patient is well	ANA 1: 680 homogeneous, proteinuria 0.18 g/24 h, complement normal, ds-DNA neg	Mycophenolate mofetil 1 g/day, prednisone 0.5 mg/kg/every other day