Journal of Immunology Research

Research Article

Complement Factor C7 Contributes to Lung Immunopathology Caused by Mycobacterium tuberculosis

Table 1

Quantitative IHC of wild-type C57BL/6 mice and C7 deficient mice infected with MTB.
ControlC7 −/−
% lung occlusion  
 Day 30 5 0 . 6 ± 1 2 . 1 4 7 . 8 ± 1 2 . 3
 Day 60 5 9 . 1 ± 1 2 . 8 4 0 . 8 ± 7 . 5 ∗
% macrophages
 Day 30 5 0 . 8 ± 1 2 . 0 3 9 . 9 ± 8 . 1
 Day 60 4 9 . 2 ± 1 3 . 1 3 0 . 3 ± 1 0 . 1 ∗
% lymphocytes
 Day 30 4 . 3 ± 2 . 8 6 . 7 ± 3 . 7
 Day 60 9 . 1 ± 3 . 1 1 7 . 0 ± 8 . 7 ∗
CD4+ lymphocytes
 Day 30 2 7 7 . 2 ± 1 2 2 . 9 3 4 8 . 9 ± 2 3 9 . 5
 Day 60 2 9 1 . 1 ± 1 5 5 . 9 9 7 3 . 9 ± 4 4 9 . 2 ∗
CD8+ lymphocytes
 Day 30 3 2 1 . 3 ± 1 7 7 . 1 4 1 7 . 3 ± 1 6 9 . 8
 Day 60 4 2 2 . 3 ± 2 8 4 . 8 4 4 0 . 3 ± 2 1 6 . 4