Genetics of Myasthenia Gravis: A Case-Control Association Study in the Hellenic Population

Table 4

IL-10 genotype frequencies in the complete cohort of MG patients (i.e., total MG), the subgroups of early and late onset MG and controls.

Phenotype	Genotypes	Total MG 𝑁=97 (%)^a	Early onset 𝑁=45 (%)^b	Late onset 𝑁=44 (%)^b	Control 𝑁=100 (%)^a
High IL-10 expression	GCC/GCC	11 (11.32)	2 (4.0)	9 (20.0)	13 (13.0)
Medium IL-10 expression	ACC/GCC	23 (23.72)	12 (27.0)	10 (23.0)	28 (28.0)
	ATA/GCC	24 (24.72)	13 (29.0)	9 (20.0)	17 (17.0)
Low IL-10 expression	ACC/ACC	12 (12.42)	5 (11.0)	6 (14.0)	15 (15.0)
	ATA/ATA	6 (6.2)	4 (9.0)	2 (5.0)	9 (9.0)
	ATA/ACC	21 (21.62)	9 (20.0)	8 (18.0)	18 (18.0)

^aAnalysis was not successful for a subset of samples.
^bEight MG samples were of unknown age at onset.