Sensitization to Cockroach Allergen: Immune Regulation and Genetic Determinants
Figure 2
TLR gene expression in cocultured pDCs and CD4+ T cells and human THP-1 cells. (a) Microarray analysis of TLR transcripts expressed in cockroach allergen (CR) and Bermuda grass allergens treated cocultured pDCs and CD4+ T cells from cockroach-sensitized and -nonsensitized subjects. Upregulated genes are represented in red and downregulated genes in green. (b) TLR expression in THP-1 cells was detected at the protein levels by FACS (red, medium; orange: nBla g2; green: CRE, 100 ug/mL; blue: Poly-IC, 50 ug/mL).
