Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus Nephritis

Table 1

Genes associated with lupus nephritis (LN) [4–10].

Gene	Function	Influence
CD48	Leucocyte adhesion	Protective effect
FcγRIIIA/IIA	Binding affinity	Susceptibility to SLE and LN
Kallikrein	Inflammation	Protective effect
IL-18	Inflammation	Susceptibility to LN
Myeloperoxidase	Inflammation	Susceptibility to LN
TLR9	Immune response	Susceptibility to LN
MBL2	Complement	Susceptibility to LN