Review Article
Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus Nephritis
Table 1
Genes associated with lupus nephritis (LN) [
4–
10].
| Gene | Function | Influence |
| CD48 | Leucocyte adhesion | Protective effect | FcγRIIIA/IIA | Binding affinity | Susceptibility to SLE and LN | Kallikrein | Inflammation | Protective effect | IL-18 | Inflammation | Susceptibility to LN | Myeloperoxidase | Inflammation | Susceptibility to LN | TLR9 | Immune response | Susceptibility to LN | MBL2 | Complement | Susceptibility to LN |
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