Journal of Immunology Research / 2012 / Article / Tab 1

Review Article

Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus Nephritis

Table 1

Genes associated with lupus nephritis (LN) [410].

GeneFunctionInfluence

CD48Leucocyte adhesionProtective effect
FcγRIIIA/IIA Binding affinitySusceptibility to SLE and LN
KallikreinInflammationProtective effect
IL-18InflammationSusceptibility to LN
Myeloperoxidase Inflammation Susceptibility to LN
TLR9Immune responseSusceptibility to LN
MBL2ComplementSusceptibility to LN

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