CD4 T-Cell-Independent Antibody Response Reduces Enterovirus 71 Lethality in Mice by Decreasing Tissue Viral Loads

Figure 2

The tissue viral loads of EV71-infected mice. The viral titers in the indicated tissues of wild-type mice (WT; 𝑛=6), B^−/− mice (𝑛=6), and CD4^−/− mice (𝑛=6) 5 days after infection are shown. The data shown are the mean values plus SE values (error bars). Viral titers that are significantly different by the Mann-Whitney U test are indicated as follows: ^∗𝑃<0.05; ^∗∗𝑃<0.01.