Restoration of Innate and Adaptive Immune Responses by HCV Viral Inhibition with an Induction Approach Using Natural Interferon-Beta in Chronic Hepatitis C
Figure 11
Rate of early viral responses in the initial 4 and 12 weeks (a) and end-of-treatment virological response and sustained virological response (b) in chronic hepatitis C patients with genotype 1 and high viral loads treated with the NCT and the SOC according to intention to treat. NCT: novel combination treatment; cyclic and periodic IFN treatment (CPIT) consisting of induction treatment with natural interferon-β followed by maintenance treatment with natural interferon-α for 24 wks as induction approach followed by SOC for 48 wks. SOC: standard of care; ribavirin plus pegylated interferon α 2b for 48 wks.
