Research Article

Polymerized-Type I Collagen Induces Upregulation of Foxp3-Expressing CD4 Regulatory T Cells and Downregulation of IL-17-Producing CD4 T Cells (Th17) Cells in Collagen-Induced Arthritis

Figure 2

Preventive effect of polymerized-type I collagen on the histological damage in CIA mice. (a) Representative section of joint histopathology is shown. Upper panel: hematoxylin and eosin stained and lower panel: PAS stained; magnification: 10x. Arrow heads point out nodules. (b) Pathology scores of each group were calculated and expressed as mean ± SEM ( ). * .
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