Macrophage Migration Inhibitory Factor in Fetoplacental Tissues from Preeclamptic Pregnancies with or without Fetal Growth Restriction

Table 2

Concentration of MIF in normal and pathological samples.

	Number of patients	Placental tissue (pg/mg)	Fetal membranes (pg/mg)	Umbilical cord tissue (pg/mg)	𝑃 value^a
Controls	8	163,8* (112,4)	87,7 (88,1)	72,3* (46,4)	*0,034
All PE	20	119,5 (80,3)	112,8 (105,5)	85,6 (58,2)	n.s.
PE-AGA	10	142,8* (94,6)	162,2° (116,7)	60,9*° (48,4)	*0,006; °0,005
PE-FGR	10	93,7 (51,9)	58,0° (54,5)	107,5° (58,5)	°0,038

PE: preeclampsia.
PE-AGA: preeclamptic pregnancies with appropriate-for-gestational-age newborns.
PE-FGR: preeclamptic pregnancies with fetal growth restriction.
n.s.: not significant.
^a𝑃 values were calculated by ANOVA test, followed by Tamhane test for pair-wise comparison.
*Comparison between placental and umbilical cord MIF concentrations.
°Comparison between fetal membranes and umbilical cord MIF concentrations.