Diminished Expression of Complement Regulatory Proteins on Peripheral Blood Cells from Systemic Lupus Erythematosus Patients

Table 2

The mean of membrane fluorescence intensity (MFI) of CD55, CD59, CD46, and CD35 on the blood cells of SLE patients and controls.

Cell	Creg	SLE patient	Control	𝑃^b
		MFI^a	MFI^a
Neutrophils	CD55	515 ± 132	611 ± 168	0.001^*
	CD59	61 ± 24	68 ± 15	0.034^*
	CD35	88 (67–154)	138 (86–185)	0.007^*
	CD46	97 ± 21	113 ±19	<0.001^**
Lymphocytes	CD55	302 ±147	350 ± 121	0.041^*
	CD59	24 (13–31)	30 (25–38)	0.012^*
	CD35	23 (21–28)	28 (21–59)	0.053
	CD46	62 (49–77)	79 (65–97)	<0.001^****
Monocytes	CD55	953 ± 313	1057 ± 241	0.021^*
	CD59	23 (18–33)	22 (15.5–33)	0.422^*
	CD46	74 ± 21	78 ± 16	0.217
	CD35	122 (66.2–202)	138 (85–198)	0.296^**
RBC	CD55	188 ± 44	201 ± 43	0.153
	CD59	73 (53–110)	112 (102.5–148)	<0.001^**
	CD35	9.1 ± 2.5	15 ± 5.0	<0.001^**

^*Significant statistical difference (P < 0.05).
^**Significant statistical difference (P < 0.001).
^aMedia ± SD or median (25–75 interquartile range).
^bMann-Whitney U test or Student’s t-test.